Alpha-fetoprotein (AFP) is a protein produced primarily during fetal development in the liver and yolk sac. AFP levels in the blood can be used to detect certain medical conditions.
AFP analysis is a blood test that measures the levels of alpha-fetoprotein in the blood. This test is most commonly used to screen for certain types of cancer, specifically liver cancer and certain types of testicular cancer. It can also be used to monitor the effectiveness of cancer treatment and to detect recurrent disease.
AFP levels can also be elevated in pregnant women, as the protein is produced by the developing fetus and crosses the placenta into the mother’s bloodstream. Elevated levels of AFP in pregnant women can be an indication of certain fetal abnormalities, such as neural tube defects or abdominal wall defects.
The AFP test is usually performed as part of a routine blood test. A healthcare provider will draw blood from a vein in the arm and send it to a laboratory for analysis. Results are typically available within a few days.
Normal AFP levels vary depending on the age and sex of the patient. In healthy adults, AFP levels are usually low or undetectable. Elevated levels may indicate the presence of cancer or other medical conditions. However, elevated levels can also occur due to non-cancerous conditions, such as cirrhosis, hepatitis, or pregnancy.
In addition to the standard AFP blood test, there are other forms of AFP analysis that can be used in certain situations. For example, amniotic fluid AFP analysis can be used to detect certain fetal abnormalities during pregnancy, and tumor marker AFP analysis can be used to monitor the effectiveness of cancer treatment.
Overall, AFP analysis is a useful tool in detecting certain medical conditions, particularly certain types of cancer. However, as with any medical test, it should be used in conjunction with other diagnostic tools and interpreted by a healthcare professional in the context of the patient’s individual medical history and symptoms.